January 22, 2019
By: Medical Team PathSOS

Latest on PSA Testing | PSA Screening for Prostate Cancer may not be Effective -PathSOS

Since its introduction in the late 1980s, PSA test has been called one of the most important screening tests for the early detection of Prostate cancer. A prostate-specific antigen (PSA) blood test measures the level of a protein called prostate-specific antigen (PSA) produced by both cancerous and noncancerous prostate tissue, which is made by cells in the prostate.

Nowadays many experts are discouraging the widespread use of PSA screening mainly in response to conflicting evidence about its benefits and harms.


What research says?


Research studies shows that PSA screening has a relatively small benefit in reducing deaths from prostate cancer ; for every 1000 men who have the PSA test, only about 1-2 men (0.1%-0.2%) will be prevented from dying of prostate cancer.  998 out of every 1000 men who have the PSA test will not benefit from it.

A recent randomised clinical trial was conducted in UK, involving a sample size of 400,000 men aged 50-69 without prostate symptoms. The findings showed no significant difference in survival between men who had a single prostate-specific antigen (PSA) test – a blood test used to detect prostate cancer – and those who didn’t, after about ten years of follow-up.


What's risky about a PSA test?


PSA is not a perfect test because it misses some cancers, which leads to over-diagnosis and over-treatment.  

There are some potential dangers of PSA. These include:

  • Worry about high numbers of false positive and sometimes false negative results which can lead to unnecessary anxiety and stress.
  • Over diagnosis and over treatment can lead to lower quality of life.
  • PSA screening do not directly detect cancer, they detect a prostate specific antigen, a protein produced by prostate cells. Conditions other than cancer sometimes can raise PSA readings, leading to painful biopsies and other invasive tests.
  • PSA screening involves time-consuming follow-up tests
  • PSA screened men can also suffer harms from the treatment, including urinary incontinence and erectile dysfunction.
  • PSA testing has always been tricky. They are not offered as standard treatment as the results can be unreliable.
  • Unnecessary expensive can cause considerable physical and psychological harm.

So what should you do?

It’s always recommended when being diagnosed with prostate cancer it’s better to get a second opinion before deciding on a course of treatment. PathSOS is a niche second opinion service that provides expert second opinion diagnostic consultation services that confirms your diagnosis and make sure that you get access to best possible treatment options.

Many people feel reluctant and resistant to seek a cancer diagnosis second opinion. Two brains are better than one. If there’s an opportunity to find an alternative and effective treatment that’s less invasive or long term, take it. 

A cancer diagnosis second opinion could correct a misdiagnosis and provide better treatment options available.

Advantages of seeking a second opinion 

  • Diagnosed with a rare type of cancer.
  • Unclear test results about the type and location of the cancer
  • You want to hear from experts for best treatment approaches
  • To help you get a better hold on your condition and give you peace of mind
  • You want different views about how to best manage the cancer.

To contact  PATHSOS call 0124 4995078 You may also visit OUR website at WWW.PATHSOS.NET